A Prospective Cohort Study of Coffee Consumption and Risk of Endometrial Cancer over a 26-Year Follow-Up.
Je Y, Hankinson SE, Tworoger SS, Devivo I, Giovannucci E.
Cancer Epidemiol Biomarkers Prev. 2011 Nov 22. [Epub ahead of print]

Authors’ Affiliations: Departments of 1Nutrition and 2Epidemiology, Harvard School of Public Health; and 3Channing Laboratory, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts.
We prospectively assessed coffee consumption in relation to endometrial cancer risk in the Nurses’ Health Study (NHS) with 67,470 female participants aged 34 to 59 in 1980. Cumulative average coffee intake was calculated with all available questionnaires to assess long-term effects..
Fewer than 4 cups of coffee per day were not associated with endometrial cancer risk. However, women who consumed 4 or more cups of coffee had 25% lower risk of endometrial cancer than those who consumed less than 1 cup per day… For decaffeinated coffee consumption, a suggestive inverse association was found among women who consumed 2 or more cups per day versus <1 cup/mo. Tea consumption was not associated with endometrial cancer risk.
These prospective data suggest that four or more cups of coffee per day are associated with a lower risk of endometrial cancer.Impact: Drinking of coffee, given its widespread consumption, might be an additional strategy to reduce endometrial cancer risk. However, addition of substantial sugar and cream to coffee could offset any potential benefits.

So, yay! Something I like turns out to be okay. Especially combined with the lowered Parkinson’s, and diabetes risk. It’s hard to imagine drinking 4 cups of caffeinated coffee a day, but maybe I should try…